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Invitrogen™ Human ULBP2 (aa 86-113) Control Fragment Recombinant Protein
Description
Highest antigen sequence indentity to the following orthologs: Mouse (43%), Rat (43%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-144940 (PA5-144940. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
ULBP2 encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6.
Spécifications
Spécifications
| Accession Number | Q9BZM5 |
| Concentration | ≥5.0 mg/mL |
| For Use With (Application) | Blocking Assay, Control |
| Formulation | 1 M urea, PBS with no preservative; pH 7.4 |
| Gene ID (Entrez) | 80328 |
| Name | Human ULBP2 (aa 86-113) Control Fragment |
| Quantity | 100 μL |
| Regulatory Status | RUO |
| Gene Alias | ALCAN-alpha; N2DL2; N2DL-2; NKG2D ligand 2; NKG2DL2; RAET1H; Retinoic acid early transcript 1 H; UL16 binding protein 2; UL16-binding protein 2; ULBP2; UNQ463/PRO791 |
| Common Name | ULBP2 |
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