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Invitrogen™ Human ULBP2 (aa 86-113) Control Fragment Recombinant Protein

Numéro de catalogue. RP109885
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100 μL
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Numéro de catalogue. Quantity
RP109885 100 μL
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Numéro de catalogue. RP109885 Fournisseur Invitrogen™ Code fournisseur RP109885
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Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (43%), Rat (43%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-144940 (PA5-144940. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

ULBP2 encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6.

Spécifications

Accession Number Q9BZM5
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 80328
Name Human ULBP2 (aa 86-113) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias ALCAN-alpha; N2DL2; N2DL-2; NKG2D ligand 2; NKG2DL2; RAET1H; Retinoic acid early transcript 1 H; UL16 binding protein 2; UL16-binding protein 2; ULBP2; UNQ463/PRO791
Common Name ULBP2
Gene Symbol ULBP2
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence AWKAQNPVLREVVDILTEQLRDIQLENY
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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