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Invitrogen™ Human UCMA Synthetic Peptide

Numéro de catalogue. PEP0882
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50 μg
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Numéro de catalogue. Quantity
PEP0882 50 μg
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Numéro de catalogue. PEP0882 Fournisseur Invitrogen™ Code fournisseur PEP0882

Description

Synthetic Peptide

This peptide corresponds to 17 amino acids near the carboxy terminus of human UCMA. PEP-0882 can be used as a blocking peptide with polyclonal antibody PA5-20768.

UCMA is a gene that encodes for a protein that is specific to chondrocytes and highly charged. This protein is expressed abundantly in the upper immature zone of fetal and juvenile epiphyseal cartilage. The encoded protein undergoes proteolytic processing to generate a mature protein that is secreted into the extracellular matrix. The glutamic acid residues in the protein undergo gamma carboxylation in a vitamin K-dependent manner. Undercarboxylation of the protein has been associated with osteoarthritis in humans. Alternative splicing of the gene results in multiple transcript variants that encode different isoforms. UCMA is also associated with diseases such as Osteoarthritis and Poland Syndrome.

Spécifications

Species Human
Purification Method purified
Accession Number Q8WVF2
Common Name UCMA
Concentration 200 μg/mL
Format Liquid
Formulation PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Gene Alias 1110017I16Rik; AW121955; C10orf49; Gla-rich protein; GRP; GRP/UCMA; RGD1308977; Ucma; ucma {ECO:0000250; Ucma-C; UniProtKB:Q14BU0}; Unique cartilage matrix-associated protein; unique cartilage matrix-associated protein {ECO:0000250; Unique cartilage matrix-associated protein C-terminal fragment; upper zone of growth plate and cartilage matrix associated; upper zone of growth plate and cartilage matrix associated protein
Gene Symbol UCMA
Lyophilized No
Preservative Sodium azide
Product Type Peptide
Quantity 50 μg
Regulatory Status RUO
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