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Invitrogen™ Human SLITRK3 (aa 762-904) Control Fragment Recombinant Protein
Description
Highest antigen sequence indentity to the following orthologs: Mouse (88%), Rat (88%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-83892 (PA5-83892. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
SLIT and NTRK-like family 3 (Slitrk3) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk3 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth.
Spécifications
Spécifications
| Accession Number | O94933 |
| Concentration | ≥5.0 mg/mL |
| For Use With (Application) | Blocking Assay, Control |
| Formulation | 1 M urea, PBS with no preservative; pH 7.4 |
| Gene ID (Entrez) | 22865 |
| Name | Human SLITRK3 (aa 762-904) Control Fragment |
| Quantity | 100 μL |
| Regulatory Status | RUO |
| Gene Alias | KIAA0848; SLIT and NTRK like family member 3; SLIT and NTRK-like family, member 3; SLIT and NTRK-like protein 3; slit and trk like gene 3; SLITRK3 |
| Common Name | SLITRK3 |
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