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Invitrogen™ Human PZP (aa 611-671) Control Fragment Recombinant Protein
Description
Highest antigen sequence indentity to the following orthologs: Mouse (51%), Rat (51%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59582 (PA5-59582. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The protein encoded by this gene is highly expressed in late-pregnancy serum and is similar in structure to alpha-2-macroglobulin. The encoded protein, which acts as a homotetramer, inhibits the activity of all four classes of proteinases. This protein contains cleavage sites for several proteinases. Upon binding of a proteinase, the conformation of this protein changes to trap the proteinase, limiting its activity. This protein appears to be elevated in the sera of presymptomatic Alzheimer's disease patients.
Spécifications
Spécifications
| Accession Number | P20742 |
| Concentration | ≥5.0 mg/mL |
| For Use With (Application) | Blocking Assay, Control |
| Formulation | 1 M urea, PBS with no preservative; pH 7.4 |
| Gene ID (Entrez) | 5858 |
| Name | Human PZP (aa 611-671) Control Fragment |
| Quantity | 100 μL |
| Gene Alias | A1m; A1m {ECO:0000312; A2m; AI893533; alpha 1 macroglobulin; alpha-1-M; Alpha-1-macroglobulin; alpha-1-macroglobulin 165 kDa subunit; Alpha-1-macroglobulin 45 kDa subunit; alpha-2-M; alpha-2-macroglobulin; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6; CPAMD6; EMBL:AAA40723.1}; MAM; Pregnancy zone protein; pregnancy-zone protein; Pzp; PZP, alpha-2-macroglobulin like |
| Common Name | PZP |
| Gene Symbol | PZP |
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