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Invitrogen™ Human Pannexin 1 Synthetic Peptide
Description
PANX1 Synthetic Peptide, PEP-1517, from Invitrogen.
The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.
Spécifications
Spécifications
| ID du gène (Entrez) | 24145 |
| Espèces | Human |
| Méthode de purification | purified |
| Numéro d'enregistrement | Q96RD7 |
| Nom usuel | Human Pannexin 1 |
| Concentration | 200 μg/mL |
| Contenu et stockage | -20°C |
| Aperçu général | Synthetic Peptide |
| Format | Liquid |
| Formule | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
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