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Invitrogen™ Human OATP2 (aa 642-665) Control Fragment Recombinant Protein

Numéro de catalogue. RP109882
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100 μL
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Numéro de catalogue. Quantity
RP109882 100 μL
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Numéro de catalogue. RP109882 Fournisseur Invitrogen™ Code fournisseur RP109882
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Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (42%), Rat (42%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-145037 (PA5-145037. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

A liver-specific member of the organic anion transporter family. This protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function.

Spécifications

Accession Number Q9Y6L6
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 10599
Name Human OATP2 (aa 642-665) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias HBLRR; liver-specific organic anion transporter 1; LST1; LST-1; OATP1B1; OATP2; OATP-2; OATPC; OATP-C; SLC01B1; SLC21A6; SLCO1B1; Sodium-independent organic anion-transporting polypeptide 2; solute carrier family 21 (organic anion transporter), member 6; Solute carrier family 21 member 6; Solute carrier organic anion transporter family member 1B1; solute carrier organic anion transporter family, member 1B1
Common Name OATP2
Gene Symbol SLCO1B1
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence ILIYAMKKKYQEKDINASENGSVM
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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