missing translation for 'onlineSavingsMsg'
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Invitrogen™ Human MAEL Synthetic Peptide
Description
This peptide corresponds to 16 amino acids near the carboxy terminus of human Maelstrom. PEP-1037 can be used as a blocking peptide with polyclonal antibody PA5-20923.
The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5'-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.
Spécifications
Spécifications
| Species | Human |
| Purification Method | purified |
| Accession Number | Q96JY0 |
| Common Name | MAEL |
| Concentration | 200 μg/mL |
| Format | Liquid |
| Formulation | PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2 |
| Gene Alias | 4933405K18Rik; AU019877; cancer/testis antigen 128; CT128; MAEL; maelstrom homolog; maelstrom homolog (Drosophila); maelstrom spermatogenic transposon silencer; protein maelstrom homolog; RGD1309333; RP11-102C16.1; SPATA35; spermatogenesis associated 35; testicular tissue protein Li 116 |
| Gene Symbol | MAEL |
| Lyophilized | No |
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