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Invitrogen™ Human FGD5 (aa 910-1049) Control Fragment Recombinant Protein

Numéro de catalogue. RP90805
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100 μL
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Numéro de catalogue. Quantity
RP90805 100 μL
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Numéro de catalogue. RP90805 Fournisseur Invitrogen™ Code fournisseur RP90805
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Description

Recombinant Protein

Highest antigen sequence indentity to the following orthologs: Mouse (74%), Rat (74%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibodies, PA5-139751 (PA5-139751, PA5-53948 (PA5-53948. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

FGD5 activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. It mediates VEGF-induced CDC42 activation. It may regulate proangiogenic action of VEGF in vascular endothelial cells, including network formation, directional movement and proliferation and may play a role in regulating the actin cytoskeleton and cell shape.

Spécifications

Accession Number Q6ZNL6
Concentration ≥5.0 mg/mL
For Use With (Application) Blocking Assay, Control
Formulation 1 M urea, PBS with no preservative; pH 7.4
Gene ID (Entrez) 152273
Name Human FGD5 (aa 910-1049) Control Fragment
Quantity 100 μL
Regulatory Status RUO
Gene Alias C330025N11Rik; Fgd5; FYVE, RhoGEF and PH domain containing 5; FYVE, RhoGEF and PH domain-containing protein 5; mFLJ00274; ZFYVE23; Zinc finger FYVE domain-containing protein 23
Common Name FGD5
Gene Symbol FGD5
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-ABP-tag
Sequence MLQHLNLDFHGAVMRALDDMDHEGRDTLAREELRQGLSELPAIHDLHQGILEELEERLSNWESQQKVADVFLAREQGFDHHATHILQFDRYLGLLSENCLHSPRLAAAVREFEQSVQGGSQTAKHRLLRVVQRLFQYQVL
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Expression System E. coli
Form Liquid
Purity or Quality Grade >80% by SDS-PAGE and Coomassie blue staining
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