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ProSci HRSP12 Recombinant Protein

Numéro de catalogue. 16594194
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Quantité:
0.05 mg
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Numéro de catalogue. Quantité
16594194 0.05 mg
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Numéro de catalogue. 16594194 Fournisseur ProSci Code fournisseur 912360050

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Recombinant Protein

This recombinant protein can be used for biological assays. For research use only.

Heat-Responsive Protein 12 (HRSP12) is an endoribonuclease that belongs to the Rut family. HRSP12 is found mainly in the human adult kidney and liver and is responsible for inhibiting protein translation by cleaving mRNA. HRSP12 only cleaves phosphodiester bonds in single-stranded RNA and inhibits cell-free protein synthesis. The levels of both mRNA and protein are markedly reduced in heptatocellular tumors and in human hepatoma cell lines compared with normal liver tissues. Moreover the levels of HRSP12 are different depending on the grade of the tumor. This had led to the suggestion that HRSP12 may be an important biomarker for heptatic carcinoma.

Spécifications

Numéro d'enregistrement P52758
À utiliser avec (application) Not Available
ID du gène (Entrez) 10247
Poids moléculaire (g/mol) 16.7 kDa
Quantité 0.05 mg
Sources E. coli
Nom usuel reactive intermediate imine deaminase A homolog
Symbole de gène RIDA
Type de produit Recombinant Protein
Conjugué Unconjugated
Espèces Human
Recombinant Recombinant
Étiquette de la protéine N-6 His tag
Contenu et stockage Store at -20°C, stable for 6 months after receipt. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Forme Lyophilized
Grade de qualité ou de pureté >95% as determined by reducing SDS-PAGE. Endotoxin level less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
Synonyme Ribonuclease UK114, 14.5 kDa Translational Inhibitor Protein, p14.5, Heat-Responsive Protein 12, UK114 Antigen Homolog, HRSP12, PSP
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