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Invitrogen™ HMGCR Polyclonal Antibody
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Numéro de catalogue. PIPA537367
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Quantité:
100 μL
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Numéro de catalogue. Quantité
PIPA537367 100 μL
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Numéro de catalogue. PIPA537367 Fournisseur Invitrogen™ Code fournisseur PA537367

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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 97 kDa. Purity is >95% by SDS-PAGE.

3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR) is a key enzyme in the mevalonate pathway, which is critical for the biosynthesis of cholesterol and other isoprenoids. HMGCR catalyzes the conversion of HMG-CoA to mevalonate, a rate-limiting step in the production of cholesterol. Due to its central role in cholesterol synthesis, HMGCR is a primary target for statin drugs, which are used to lower cholesterol levels and reduce the risk of cardiovascular disease.

Spécifications

Antigène HMGCR
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugué Unconjugated
Formule PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gène HMGCR
Numéro d’acquisition du gène P04035, P51639, Q01237
Alias du gène 3H3M; 3-hydroxy-3-methylglutaryl CoA reductase (NADPH); 3-hydroxy-3-methylglutaryl-CoA reductase; 3-hydroxy-3-methylglutaryl-Coenzyme A reductase; HMDH; HMG CoA reductase; HMG CoAR; HMG-CoA reductase; HMG-CoAR; HMGCR; hydroxymethylglutaryl-CoA reductase; LDLCQ3; MGC103269; Red
Symboles de gène HMGCR
Espèces hôtes Rabbit
Immunogène Recombinant full length human HMGCR.
Méthode de purification Antigen affinity chromatography
Quantité 100 μL
Statut réglementaire RUO
Primaire ou secondaire Primary
ID du gène (Entrez) 15357, 25675, 3156
Espèces cibles Human, Mouse, Rat
Contenu et stockage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Type de produit Antibody
Forme Liquid
Isotype IgG
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