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  5. Tocris Bioscience™ GNF 5

Tocris Bioscience™ GNF 5

Catalog No. 490810
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50 mg
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490810 10 mg
490850 50 mg
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Catalog No. 490810 Supplier Tocris Bioscience™ Supplier No. 4908/10
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Description

Selective allosteric inhibitor of Bcr-Abl; analog of GNF 2 (Cat. No. 4399)

Selective, non-ATP competitive allosteric inhibitor of Bcr-Abl (IC50 = 220 nM for wild-type Abl). Binds the myristate-binding site of Abl. Acts in combination with nilotinib to inhibit T315I Bcr-Abl in vitro and in vivo. Analog of GNF 2 (Cat. No. 4399).

Chemical Identifiers

CAS 778277-15-9
Molecular Formula C20H17F3N4O3

Specifications

Quantity 10 mg
Formula Weight 418.37
Molecular Weight (g/mol) 418.376
Chemical Name or Material GNF 5

Safety and Handling

Recommended Storage Store at +4°C