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Invitrogen™ FUS Monoclonal Antibody (1FU-1D2)

Description
MA3-089 detects AID from human samples MA3-089 has been successfully used in Western blot. The MA3-089 immunogen is the synthetic peptide coupled to ovalalbumin, aa 266 to 283. MA3-089 detects FUS/TLS (~70kDa) in human samples.
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.
Specifications
Specifications
| Antigen | FUS |
| Applications | Western Blot, Immunocytochemistry |
| Classification | Monoclonal |
| Clone | 1FU-1D2 |
| Concentration | Conc. Not Determined |
| Conjugate | Unconjugated |
| Formulation | Ascites with 0.05% sodium azide |
| Gene | FUS |
| Gene Accession No. | P35637 |
| Gene Alias | 16) in malignant liposarcoma); 16) malignant liposarcoma; 75 kDa DNA-pairing protein; ALS6; D430004D17Rik; D930039C12Rik; ETM4; FUS; FUS RNA binding protein; Fus1; fused in sarcoma; fused in sarcoma RNA binding protein; fusion (involved in t(12; fusion gene in myxoid liposarcoma; fusion, derived from t(12; fusion, derived from t(12;16) malignant liposarcoma; fus-like protein; heterogeneous nuclear ribonucleoprotein P2; hnRNP P2; HNRNPP2; oncogene FUS; Oncogene TLS; pigpen protein; POMP75; Protein pigpen; RNA-binding protein FUS; TLS; translocated in liposarcoma; translocated in liposarcoma protein |
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