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Fumonisin B2, 96+%, Thermo Scientific™
Fumonisin B2, CAS # 116355-84-1, is a diester of tricarballylic acid and is isolated from Fusarium.
Supplier: Thermo Scientific Chemicals 328260010
| Quantity | 1mg |
|---|
Description
This Thermo Scientific brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
General Description
• Fumonisin B2 is a fumonisin mycotoxin produced by the fungus Fusarium
• Fumonisin B2 is a structural analog of fumonisin B1 but it is more cytotoxic than B1 and can inhibit sphinganine-N-acetyltransferase (ceramide synthase)
Applications
• In vitro and in vivo studies have shown Fumonisin B2 can induce apoptosis
• It can inhibit de novo sphingolipid biosynthesis
• It is also considered an Aspergillus metabolite
• It shows cytotoxicity against a panel of seven rat hepatoma cell lines, and MDCK cell line
• It induces hepatocyte nodule formation, a marker of cancer initiation, in rats
Chemical Identifiers
| 116355-84-1 | |
| 759.9 | |
| fumonisin b2, 2r,2'r-1,2,3-propanetricarboxylic acid 1,1'-1s,2r-1-2s,9r,11s,12s-12-amino-4,9,11-trihydroxy-2-methyltridecyl-2-1r-1-methylpentyl-1,2-ethanediyl ester, 2s-2-2-5r,6r,7s,9s,16r,18s,19s-19-amino-6-3r-3,4-dicarboxybutanoyl oxy-16,18-dihydroxy-5,9-dimethylicosan-7-yl oxy-2-oxoethyl butanedioic acid | |
| (2S)-2-[2-[(5R,6R,7S,9S,16R,18S,19S)-19-amino-6-[(3R)-3,4-dicarboxybutanoyl]oxy-16,18-dihydroxy-5,9-dimethylicosan-7-yl]oxy-2-oxoethyl]butanedioic acid |
| C34H59NO14·3H2O | |
| UXDPXZQHTDAXOZ-FWPUDPCBSA-N | |
| 71317007 | |
| CCCCC(C)C(C(CC(C)CCCCCCC(CC(C(C)N)O)O)OC(=O)CC(CC(=O)O)C(=O)O)OC(=O)CC(CC(=O)O)C(=O)O |
Specifications
| Fumonisin B2 | |
| 96+% | |
| 1mg | |
| Solubility in water: .. Other solubilities: soluble in methanol | |
| CCCCC(C)C(C(CC(C)CCCCCCC(CC(C(C)N)O)O)OC(=O)CC(CC(=O)O)C(=O)O)OC(=O)CC(CC(=O)O)C(=O)O | |
| 759.9 | |
| 759.9 |
| 116355-84-1 | |
| C34H59NO14·3H2O | |
| fumonisin b2, 2r,2'r-1,2,3-propanetricarboxylic acid 1,1'-1s,2r-1-2s,9r,11s,12s-12-amino-4,9,11-trihydroxy-2-methyltridecyl-2-1r-1-methylpentyl-1,2-ethanediyl ester, 2s-2-2-5r,6r,7s,9s,16r,18s,19s-19-amino-6-3r-3,4-dicarboxybutanoyl oxy-16,18-dihydroxy-5,9-dimethylicosan-7-yl oxy-2-oxoethyl butanedioic acid | |
| UXDPXZQHTDAXOZ-FWPUDPCBSA-N | |
| (2S)-2-[2-[(5R,6R,7S,9S,16R,18S,19S)-19-amino-6-[(3R)-3,4-dicarboxybutanoyl]oxy-16,18-dihydroxy-5,9-dimethylicosan-7-yl]oxy-2-oxoethyl]butanedioic acid | |
| 71317007 | |
| 96+% |
Safety and Handling
GHS Signal Word: Danger