missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Anticorps
  4. Panels et kits d’anticorps
  5. 5016974

Invitrogen™ Anti-Human Foxp3 Staining Set PE, eBioscience™

Numéro de catalogue. 5016974
Modifier l'affichage
Click to view available options
Quantité:
1 kit
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Numéro de catalogue. Quantité
5016974 1 kit
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Numéro de catalogue. 5016974 Fournisseur Invitrogen™ Code fournisseur 72577440

Pour de l'aide SVP utiliser la function de clavardage; nous envoyer un couriel à help@thermofisher.com ou appelez le service à la clientèle au 1-800-234-7437.

Description

Comprend

  • Fixation/Permeabilization Concentrate (4X) (cat. 00-5123): 30mL, store at 2-8°C. Avoid agitation.
  • Fixation/Permeabilization Diluent (cat. 00-5223): 100mL, store at 2-8°C.
  • Permeabilization Buffer (10X) (cat. 00-8333): 100mL, store at 2-8°C. Note: The 10X Permeabilization Buffer has a natural tendency to precipitate, however, its function is not affected by this. To clarify, the solution can be filtered after dilution to 1x working solution.
  • Normal Mouse Serum (cat. 24-5544): 100 μL, store at 2-8°C.
  • Anti-Human Foxp3 PE (clone 236A/E7, cat. 12-4777): 25 tests, store at 2-8°C. Light-sensitive material.

Antibody Staining Kit

This Anti-Human Foxp3 Staining Set contains the buffers and monoclonal antibody necessary to successfully stain and identify Foxp3+ cells. The 236A/E7 monoclonal antibody reacts with human Foxp3, also known as FORKHEAD BOX P3, SCURFIN, and JM2. Foxp3 is a 49-55kDa protein and a member of the forkhead/winged-helix family of transcription factors. It was identified as the gene responsible for the X-linked lymphoproliferative disease observed in scurfy (sf) mice and in the human disorder, X-linked autoimmunity-allergic dysregulation syndrome (XLAAD). Constitutive expression of Foxp3 mRNA has been shown in CD4+CD25+ regulatory T cells (Treg), and ectopic expression of Foxp3 in CD4+CD25- cells imparts a Treg phenotype in these cells.

The 236A/E7 antibody has been shown to crossreact with rhesus macaque, sooty mangabey, and cynomolgus Foxp3. 236A/E7 recognizes a different epitope of Foxp3 than PCH101 and 150D/E4.

Spécifications

Antigène Foxp3
Applications Flow Cytometry
Classification Monoclonal
Clone 236A/E7
Conjugué PE
Alias du gène Forkhead Box P3, Scurfin, JM2
Espèces hôtes Mouse
Quantité 1 kit
Statut réglementaire RUO
Primaire ou secondaire Primary
Espèces cibles Cynomolgus, Human, Macaque, Monkey, Non-human Primate, Rhesus Monkey
Contenu et stockage Store at 2-8°C. Light sensitive material. Use within 6 months of opening or by date indicated on the bottle.
Isotype IgG1
Gamme de produit eBioscience
Afficher plus de résultats Afficher moins de résultats

For Research Use Only. Not for use in diagnostic procedures.