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  5. Tocris Bioscience™ Fludarabine

Tocris Bioscience™ Fludarabine

Numéro de catalogue. 349550
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50 mg
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Numéro de catalogue. Quantité
349550 50 mg
349510 10 mg
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Numéro de catalogue. 349550 Fournisseur Tocris Bioscience™ Code fournisseur 3495/50
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Description

Purine analog; inhibits DNA synthesis

Purine analog that inhibits DNA synthesis. Exhibits antiproliferative activity (IC50 = 1.54 μM in RPMI cells) and triggers apoptosis through increasing Bax and decreasing Bid, XIAP and survivin expression. Inhibits cytokine-induced activation of STAT1 and STAT1-dependent gene transcription in lymphocytes. Also displays anticancer activity against hematological malignancies in vivo.

Identifiants chimiques

CAS 21679-14-1
Formule moléculaire C10H12FN5O4

Spécifications

Nom ou substance chimique Fludarabine
Quantité 50 mg
Poids de formule 285.23
Pureté >99%
Poids moléculaire (g/mol) 285.24

Sécurité et manipulation

Recommended Storage Desiccate at +4°C