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Ethidium bromide soln., 10mg/ml

Catalog No. AAJ62282AB
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AAJ62282AB 10 mL
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Catalog No. AAJ62282AB Supplier Thermo Scientific Chemicals Supplier No. J62282AB
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Description

CAS: 1239-45-8 | C21H20BrN3 | 394.32 g/mol

Ethidium bromide has been used in a number of fluorimetric assays for nucleic acids.1,2,3 It has been shown to bind to single-stranded DNA (although not as strongly) and triple-stranded DNA.4 Because of its ability to bind to DNA, EtBr is an inhibitor of DNA polymerase. Ethidium bromide intercalates double-stranded DNA and RNA and acts as a frameshift mutagen. It can also be used in conjunction with acridine orange to differentiate between viable, apoptotic and necrotic cells.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Chemical Identifiers

CAS 1239-45-8
Molecular Formula C21H20BrN3
Molecular Weight (g/mol) 394.32
MDL Number MFCD00011724
InChI Key ZMMJGEGLRURXTF-UHFFFAOYSA-N
Synonym ethidium bromide, homidium bromide, dromilac, 3,8-diamino-5-ethyl-6-phenylphenanthridinium bromide, ethydium bromide, 3,8-diamino-5-ethyl-6-phenylphenanthridin-5-ium bromide, etbr, 2,7-diamino-10-ethyl-9-phenylphenanthridinium bromide, 2,7-diamino-9-phenyl-10-ethylphenanthridinium bromide, unii-059nuo2z1l
PubChem CID 14710
ChEBI CHEBI:4883
IUPAC Name 5-ethyl-6-phenylphenanthridin-5-ium-3,8-diamine;bromide
SMILES [Br-].CC[N+]1=C(C2=CC=CC=C2)C2=CC(N)=CC=C2C2=CC=C(N)C=C12

Specifications

Color Red
UN Number UN2810
Concentration 10mg/ml
Merck Index 14,4731
Solubility Information Soluble in water (10mg/mL).
Formula Weight 394.32
Odor Odorless
Quantity 10 mL
Physical Form Liquid
Chemical Name or Material Ethidium bromide soln.

Safety and Handling

Hazard Category H331-H341
Hazard Statement GHS H Statement
H341
Suspected of causing genetic defects.
Precautionary Statement P201-P202-P261-P271-P281-P304+P340-P308+P313-P311-P501c
DOTInformation Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC, LIQUIDS, ORGANIC, N.O.S.
EINECSNumber 214-984-6
RTECSNumber SF7950000
TSCA No
Recommended Storage Ambient temperatures

RUO – Research Use Only