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Invitrogen™ eIF3b Recombinant Rabbit Monoclonal Antibody (23GB6260)
Rabbit Recombinant Monoclonal Antibody
Spécifications
| Antigen | eIF3b |
|---|---|
| Clone | 23GB6260 |
| Content And Storage | -20°C |
| Applications | Flow Cytometry, Western Blot, Immunocytochemistry |
| Classification | Recombinant Monoclonal |
| Numéro de catalogue | Numéro du manufacturier. | Quantity | Prix | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Numéro de catalogue | Numéro du manufacturier. | Quantity | Prix | Quantity & Availability | |||||
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MA553008
|
Invitrogen™
MA553008 |
100 μL |
N/A
|
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Connectez-vous ou enregistrez-vous pour vérifier votre prix et la disponibilité.
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|
MA553009
|
Invitrogen™
MA553009 |
20 μL |
N/A
|
|
Connectez-vous ou enregistrez-vous pour vérifier votre prix et la disponibilité.
|
||||
Description
eIF3b Recombinant Monoclonal Antibody for Flow, ICC/IF, Western Blot
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:9388245, PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:9388245, PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773). [UniProt].Spécifications
| eIF3b | |
| -20°C | |
| Recombinant Monoclonal | |
| Liquid | |
| IgG | |
| Human, Mouse, Rat | |
| EIF3B | |
| AL033316; AL033334; AL033369; AW208965; D5Wsu45e; eIF3 p110; eIF3 p116; EIF3B; eIF3b {ECO:0000255; eIF-3-eta; EIF3-ETA; eIF-3-eta {ECO:0000255; EIF3-P110; EIF3-P116; EIF3S9; eukaryotic translation initiation factor 3 subunit 9; eukaryotic translation initiation factor 3 subunit 9 {ECO:0000255; Eukaryotic translation initiation factor 3 subunit B; eukaryotic translation initiation factor 3 subunit B {ECO:0000255; eukaryotic translation initiation factor 3, subunit 9 (eta); eukaryotic translation initiation factor 3, subunit 9 (eta, 116kD); eukaryotic translation initiation factor 3, subunit 9 eta, 116kDa; eukaryotic translation initiation factor 3, subunit B; HAMAP-Rule:MF_03001}; hPrt1; MGC104664; MGC131875; PRT1; Prt1 homolog | |
| EIF3B | |
| Primary | |
| Affinity chromatography |
| 23GB6260 | |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P55884, Q4G061, Q8JZQ9 | |
| 27979, 288516, 8662 | |
| A synthesized peptide derived from human HPRT (164-218AA). | |
| Antibody |