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Invitrogen™ DLL4 (delta-like 4) Polyclonal Antibody
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Numéro de catalogue. PIPA585931
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Quantité:
100 μL
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Numéro de catalogue. Quantité
PIPA585931 100 μL
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Numéro de catalogue. PIPA585931 Fournisseur Invitrogen™ Code fournisseur PA585931

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Description

Rabbit Polyclonal Antibody

DLL4 (delta-like 4) Polyclonal Antibody for Flow, ICC/IF, IHC (P), Western Blot

Delta-like ligand 4 (DLL4), also know as Delta-4, is a homologue of the Drosophila delta protein, and functions as a transmembrane bound ligand to the notch receptor Notch1. DLL4 is expressed in the vasculature and plays a critical role in vascular development. It is induced by vascular endothelial growth factor (VEGF), as a negative feedback regulator to regulate angiogenic sprouting and promote the formulation of a differentiated vascular network. DLL4 has been found to be strongly expressed in tumor vessels of clear-cell renal tumors and bladder cancer, and inhibition of DLL4 results in increased vascular proliferation but defective maturation. This in turn leads to a decrease in tumor growth, with no apparent toxicity.

Spécifications

Antigène DLL4 (delta-like 4)
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugué Unconjugated
Formule PBS with 0.2% BSA, 50% Glycerol and 0.05% sodium azide; pH 7.4
Gène Dll4
Numéro d’acquisition du gène Q9JI71, Q9NR61
Alias du gène AOS6; delta 4; delta ligand 4; delta like canonical Notch ligand 4; Delta4; delta-like 4 (Drosophila); delta-like 4 homolog; delta-like 4 protein; delta-like protein 4; DLL4; Drosophila Delta homolog 4; hdelta2; MGC126344; notch ligand delta-2; notch ligand DLL4; UNQ1895/PRO4341
Symboles de gène Dll4
Espèces hôtes Rabbit
Immunogène Recombinant protein within Human DLL4 aa 175-370.
Méthode de purification Protein A
Quantité 100 μL
Statut réglementaire RUO
Primaire ou secondaire Primary
ID du gène (Entrez) 54485, 54567
Espèces cibles Human, Mouse
Contenu et stockage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Type de produit Antibody
Forme Liquid
Isotype IgG
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