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Tocris Bioscience™ DIDS
Description
ClC-Ka chloride channel blocker (IC50 = 100 μM). Blocks the maxi chloride channel in apical membranes from human placenta. Displays antagonistic activity at TRPM4 and TRPC4 channels; potentiates agonist-induced TRPV1 currents (IC50 = 4.88 μM in rat DRG neurons). Inhibits RAD51 recombinase activity (KD = 2 μM).
Specifications
Specifications
| Quantity | 50 mg |
| Formula Weight | 498.48 |
| Purity | >95% |
| Molecular Weight (g/mol) | 498.468 |
| Chemical Name or Material | DIDS |
Safety and Handling
| Recommended Storage | Store at +4°C |