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Dextran Sulfate Sodium Salt, Colitis Grade (36,000 to 50,000), MP Biomedicals™

Induces severe colitis (inflammatory bowel disease) in laboratory animals

$543.86 - $11479.96

Specifications

Color White
pH 5 to 7.11 (1% aqueous solution)
CAS 9011-18-1
Physical Form Powder
Boiling Point 310°C
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Products 5
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
ICN16011010
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MP Biomedicals Inc
0216011010
10 g
Each for $543.86
 
MP216011025
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MP Biomedicals Inc
0216011025
25 g
Each for $899.86
 
ICN16011050
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MP Biomedicals Inc
0216011050
50 g
Each for $1,652.72
 
ICN16011080
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MP Biomedicals Inc
0216011080
100 g
Each for $2,654.51
 
ICN16011090
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MP Biomedicals Inc
0216011090
500 g N/A
N/A
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Description

Description

Induces severe colitis (inflammatory bowel disease) in laboratory animals

Dextran sulfate sodium salt, or DSS, is a synthetic sulfated branched polysaccharide derivative of dextran that has multiple uses in biomedical and clinical research. One important property of DSS is to trigger colitis in mice and rats when administered in drinking water. DSS binds to medium-chain-length fatty acids in the colon and induces intestinal inflammation. Colitis-grade DSS (MW = 36,000 to 50,000) from MP Bio is one of the most widely used products based on peer reviewed scientific publications.

  • Induces severe colitis (inflammatory bowel disease)
  • Highest sulfur content – 19%
  • Highest chirality - +104° of specific rotation
  • Lowest pH – 6.2 at 1% solution
Specifications

Specifications

White
9011-18-1
310°C
MFCD00081551
Colitis Grade
<10%
5 to 7.11 (1% aqueous solution)
Powder
92°C
Soluble in water
Used for inducing ulcerative colitis in animals and extensively to study colon cancer developing in relation to colonic inflammation
Plastic Container
SDS
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Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use.