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Dextran Sulfate Sodium Salt, Colitis Grade (36,000 to 50,000), MP Biomedicals™

Catalog No. MP216011025
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Catalog No. Quantity
MP216011025 25 g
ICN16011010 10 g
ICN16011050 50 g
ICN16011080 100 g
ICN16011090 500 g
0216011091 1000 g
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Catalog No. MP216011025

Supplier: MP Biomedicals Inc 0216011025

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Description

Induces severe colitis (inflammatory bowel disease) in laboratory animals

Dextran sulfate sodium salt, or DSS, is a synthetic sulfated branched polysaccharide derivative of dextran that has multiple uses in biomedical and clinical research. One important property of DSS is to trigger colitis in mice and rats when administered in drinking water. DSS binds to medium-chain-length fatty acids in the colon and induces intestinal inflammation. Colitis-grade DSS (MW = 36,000 to 50,000) from MP Bio is one of the most widely used products based on peer reviewed scientific publications.

  • Induces severe colitis (inflammatory bowel disease)
  • Highest sulfur content – 19%
  • Highest chirality - +104° of specific rotation
  • Lowest pH – 6.2 at 1% solution

Specifications

Color White
Chemical Name or Material Dextran Sulfate Sodium Salt
pH 5 to 7.11 (1% aqueous solution)
Physical Form Powder
CAS 9011-18-1
Boiling Point 310°C
Melting Point 92°C
Molecular Formula (C6H7O5)m(C6H7O5)n
MDL Number MFCD00081551
Solubility Information Soluble in water
Quantity 25 g
InChI Key BLFLLBZGZJTVJG-UHFFFAOYSA-N
SMILES *-OC[C@H]1O[C@H](OC[C@H]2O[C@H](-*)[C@H](O[*])[C@@H](O[*])[C@@H]2O[*])[C@H](O[*])[C@@H](O-*)[C@@H]1O[*]
IUPAC Name Dextran sulfate sodium salt
Molecular Weight (g/mol) 40,000
For Use With (Application) Used for inducing ulcerative colitis in animals and extensively to study colon cancer developing in relation to colonic inflammation
Grade Colitis Grade
Moisture <10%
Packaging Plastic Container
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Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use.