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ProSci Death Receptor 6 Recombinant Protein

Numéro de catalogue. 16594204
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Quantité:
0.05 mg
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Numéro de catalogue. Quantité
16594204 0.05 mg
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Numéro de catalogue. 16594204 Fournisseur ProSci Code fournisseur 913030050

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Description

Recombinant Protein

This recombinant protein can be used for biological assays. For research use only.

Tumor Necrosis Factor Receptor Superfamily Member 21 (TNFRSF21) is a type I transmembrane receptor that includes four extracellular cysteine-rich motifs and a cytoplasmic death domain. DR6 is highly expressed in heart, brain, placenta, pancreas, lymph node, thymus and prostate. DR6 may activate NF-kappa-B and JNK to promote apoptosis and T-cell differentiation. In addition, DR6 binds with N-APP, which is released by the deprivation of Trophic-factor. It triggers caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6). DR6 is also expressed on the tumor cell lines and can be induced by TNF- alpha.

Spécifications

Numéro d'enregistrement O75509
À utiliser avec (application) Not Available
ID du gène (Entrez) 27242
Poids moléculaire (g/mol) 34.62 kDa
Quantité 0.05 mg
Sources Human Cells
Nom usuel tumor necrosis factor receptor superfamily member 21
Symbole de gène TNFRSF21
Type de produit Recombinant Protein
Conjugué Unconjugated
Espèces Human
Recombinant Recombinant
Étiquette de la protéine C-6 His tag
Contenu et stockage Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4°C to 7°C for 2-7 days. Aliquots of reconstituted samples are stable (at -20°C for 3 months.)
Forme Lyophilized
Grade de qualité ou de pureté >95% as determined by reducing SDS-PAGE. Endotoxin level less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
Synonyme Tumor Necrosis Factor Receptor Superfamily Member 21, Death Receptor 6, CD358, TNFRSF21, DR6
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