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Cytochalasin B

Numéro de catalogue. AAJ65342MA
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AAJ65342MA 10 mg
AAJ65342LB0 5 mg
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Numéro de catalogue. AAJ65342MA Fournisseur Thermo Scientific Chemicals Code fournisseur J65342MA
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Description

An actin-disrupting agent | CAS: 14930-96-2 | C29H37NO5 | 479.62 g/mol

Cytochalasin B is used for characterizing some of the polymerization properties of actin, and in studies on cytokinesis. Probe for the two hexose-transport systems in rat L6 myoblasts. And induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Cytochalasin B is used for characterizing some of the polymerization properties of actin, and in studies on cytokinesis. Probe for the two hexose-transport systems in rat L6 myoblasts. And induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport.

Solubility
Freely soluble in DMF, DMSO or ethanol at room temperature

Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Identifiants chimiques

CAS 14930-96-2
Molecular Formula C29H37NO5
Molecular Weight (g/mol) 479.62
MDL Number MFCD00077704
InChI Key GBOGMAARMMDZGR-UHFFFAOYNA-N
Synonym cytochalasin b, cytochalasin b from helminthosporium dematioideum
PubChem CID 44634701
IUPAC Name 16-benzyl-5,13-dihydroxy-9,15-dimethyl-14-methylidene-2H,5H,6H,7H,8H,9H,10H,12aH,13H,14H,15H,15aH,16H,17H,18H-oxacyclotetradeca[3,2-e]isoindole-2,18-dione
SMILES CC1C2C(CC3=CC=CC=C3)NC(=O)C22OC(=O)C=CC(O)CCCC(C)CC=CC2C(O)C1=C

Spécifications

Melting Point 218°C to 221°C
Color White
Odor Odorless
Quantity 10 mg
UN Number UN1544
Beilstein 1096207
Merck Index 14,2790
Solubility Information Freely soluble in DMF, DMSO or ethanol at room temperature
Formula Weight 479.61
Physical Form Powder
Chemical Name or Material Cytochalasin B
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Sécurité et manipulation

Hazard Category H300+H310+H330-H361
Hazard Statement GHS H Statement
H300-H310-H330-H361
Fatal if swallowed.
Fatal in contact with skin.
Fatal if inhaled.
Suspected of damaging fertility or the unborn child.
Precautionary Statement P201-P202-P260-P262-P264b-P270-P271-P281-P284-P301+P310-P302+P350-P304+P340-P308+P313-P310-P330-P361-P363-P501c
DOTInformation Hazard Class: 6.1; Packaging Group: III
EINECSNumber 239-000-2
RTECSNumber RO0205000
TSCA No
Recommended Storage Store at -20°C

RUO – Research Use Only