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Coenzyme Q-10, 98+%

Catalog No. AAJ6513703
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Quantity:
1 g
25 g
5 g
Catalog No. Quantity
AAJ6513703 1 g
AAJ6513706 5 g
AAJ6513714 25 g
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Catalog No. AAJ6513703

Supplier: Thermo Scientific Chemicals J6513703

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Description

Component of electron transport chain and in aerobic cellular respiration | CAS: 303-98-0 | C59H90O4 | 863.37 g/mol

It is used as a component of electron transport chain and in aerobic cellular respiration, Coenzyme Q10 can protect human endothelial cells from oxidative damage by modulating the nitric oxide pathway. In addition, Coenzyme Q10 inhibits LDL oxidation, a major process in the development of atherosclerosis. Coenzyme Q10 is known to suppress the down regulation of NOS and up-regulation of NOS2. As a result of its ability to bind Ca2+, Coenzyme Q10 can transport this cation across artificial biomimetic membranes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is used as a component of electron transport chain and in aerobic cellular respiration, Coenzyme Q10 can protect human endothelial cells from oxidative damage by modulating the nitric oxide pathway. In addition, Coenzyme Q10 inhibits LDL oxidation, a major process in the development of atherosclerosis. Coenzyme Q10 is known to suppress the down regulation of NOS and up-regulation of NOS2. As a result of its ability to bind Ca2+, Coenzyme Q10 can transport this cation across artificial biomimetic membranes.

Solubility
Soluble in chloroform.

Notes
Light Sensitive. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Chemical Identifiers

CAS 303-98-0
Molecular Formula C59H90O4
Molecular Weight (g/mol) 863.37
MDL Number MFCD00042919
InChI Key ACTIUHUUMQJHFO-UPTCCGCDSA-N
Synonym coenzyme q10, ubidecarenone, ubiquinone 50, coq10, ubiquinone-10, neuquinon, ubiquinone, justquinon, neuquinone, emitolon
PubChem CID 5281915
ChEBI CHEBI:46245
SMILES COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O

Specifications

Melting Point 48°C to 52°C
Color Yellow to Orange
Quantity 1 g
Beilstein 1900141
Sensitivity Light sensitive
Merck Index 14,9843
Solubility Information Soluble in chloroform.
IUPAC Name 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl]-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione
Formula Weight 863.36
Percent Purity ≥98%
Physical Form Powder
Chemical Name or Material Coenzyme Q-10
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Safety and Handling

EINECSNumber 206-147-9
RTECSNumber DK3900000
TSCA Yes
Recommended Storage Store at -20°C

RUO – Research Use Only