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Tocris Bioscience™ Clozapine N-oxide

Catalog No. 493650
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493610 10 mg
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Catalog No. 493650 Supplier Tocris Bioscience™ Supplier No. 4936/50
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Description

Activator of muscarinic DREADDs

Metabolite of clozapine (Cat. No. 0444). Activates human muscarinic designer receptors (DREADDs) in vitro. Silences hippocampal neurons expressing hM4 DREADDs in vitro. Activates Gs-linked DREADDS- AgRP in mice via intracerebroventricular (i.c.v) injection. Shown to be a P-glycoprotein (P-gp) efflux pump substrate. Other potent and selective hM3Dq DREADD agonists available: DREADD agonist 21 and Perlapine .

Water soluble salt also available.

This product contains 1 molar equivalent of ethanol.

Chemical Identifiers

CAS 34233-69-7
Molecular Formula C18H19ClN4O

Specifications

Assay Percent Range >98%
Quantity 50 mg
Formula Weight 342.82
Purity >99%
Molecular Weight (g/mol) 342.827
Chemical Name or Material Clozapine N-oxide

Safety and Handling

Recommended Storage Store at Room Temperature