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Invitrogen™ CAS Recombinant Rabbit Monoclonal Antibody (23GB3515)

Numéro de catalogue. MA553427
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20 μL
100 μL
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Numéro de catalogue. Quantity
MA553427 20 μL
MA553426 100 μL
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Numéro de catalogue. MA553427 Fournisseur Invitrogen™ Code fournisseur MA553427
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Rabbit Recombinant Monoclonal Antibody

CAS Recombinant Monoclonal Antibody for Western Blot, ICC/IF, Flow

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation.

Spécifications

Antigen CAS
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 23GB3515
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CSE1L
Gene Accession No. P55060, Q9ERK4
Gene Alias 2610100P18Rik; AA407533; Capts; CAS; Cellular apoptosis susceptibility protein; chromosome segregation 1 like; chromosome segregation 1-like (S. cerevisiae); chromosome segregation 1-like protein; CSE1; CSE1 chromosome segregation 1 like; CSE1 chromosome segregation 1-like; CSE1 chromosome segregation 1-like (yeast); CSE1L; Exp2; exportin-2; Importin-alpha re-exporter; MGC117283; MGC130036; MGC130037; XPO2
Gene Symbols CSE1L
Host Species Rabbit
Immunogen A synthetic peptide of human Exportin2 (900-971AA).
Purification Method Affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 110750, 1434, 362273
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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