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Invitrogen™ Calreticulin Polyclonal Antibody
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Numéro de catalogue. PA1902A
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Quantité:
100 μL
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Numéro de catalogue. Quantité
PA1902A 100 μL
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Numéro de catalogue. PA1902A Fournisseur Invitrogen™ Code fournisseur PA1902A

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Description

Chicken Polyclonal Antibody

PA1-902A detects calreticulin from canine, hamster, human, mouse and rat tissues. PA1-902A has been successfully used in Western blot, immunocytochemistry and immunofluorescene procedures. By Western blot, this antibody detects an ~60-66 kDa protein representing calreticulin. PA1-902A immunizing peptide corresponds to amino acid residues 24-43 from mouse calreticulin. PA1-902A immunizing peptide (Cat. # PEP-018) is available for use in neutralization and control experiments.

Calr or Calreticulin is a calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. Calr, a lectin, interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Calr also interacts with with the DNA-binding domain of NR3C1 and mediates its nuclear export. It may also be involved in maternal gene expression regulation and oocyte maturation via the regulation of calcium homeostasis.

Spécifications

Antigène Calreticulin
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.1 mg/mL
Conjugué Unconjugated
Formule PBS with 1mg/mL BSA and 0.05% sodium azide
Gène CALR
Numéro d’acquisition du gène P14211, P18418, P27797, P28490, Q8K3H7
Alias du gène Autoantigen RO; CABP3; CALBP; calcium-binding protein 3; CALR; calrectulin; calregulin; Calreticulin; calreticulin precursor; cC1qR; CRP55; CRT; CRTC; Endoplasmic reticulum resident protein 60; epididymis secretory sperm binding protein Li 99n; ERp60; FLJ26680; grp60; HACBP; HEL-S-99n; I79_008346; RO; Ro/SS-A Antigen; Sicca syndrome antigen A (autoantigen Ro; calreticulin); SSA
Symboles de gène CALR
Espèces hôtes Chicken
Immunogène Synthetic Peptide: K(24) E Q F L D G D A W T N R W V E S K H K(43).
Méthode de purification Antigen affinity chromatography
Quantité 100 μL
Statut réglementaire RUO
Primaire ou secondaire Primary
ID du gène (Entrez) 100689096, 12317, 476694, 64202, 811
Espèces cibles Human, Mouse, Rat, Canine, Hamster
Contenu et stockage -20°C, Avoid Freeze/Thaw Cycles
Type de produit Antibody
Forme Liquid
Isotype IgY
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