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  6. MilliporeSigma™ Calbiochem™ Nα-Tosyl-Lys Chloromethyl Ketone, Hydrochloride

MilliporeSigma™ Calbiochem™ Nα-Tosyl-Lys Chloromethyl Ketone, Hydrochloride

Catalog No. 616382250MG
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250 mg
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616382250MG 250 mg
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Catalog No. 616382250MG Supplier MilliporeSigma™ Supplier No. 616382250MG
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Description

Inhibits trypsin-like serine proteinases.

Inhibits trypsin-like serine proteinases. Irreversibly inactivates trypsin without affecting chymotrypsin. Prevents nitric oxide production by activated macrophages by interfering with transcription of the iNOS gene. Blocks cell-cell adhesion and binding of HIV-1 virus to the target cells. In macrophages, blocks nitric oxide synthase induced by interferon-γ and lipopolysaccharides (EC50 = 80μM). Prevents endonucleolysis accompanying apoptotic death of HL-60 leukemia cells and normal thymocytes.

Specifications

Color Off-white
Target Proteins trypsin like proteases
CAS 4238-41-9
Molecular Formula C14H21ClN2O3S·HCl
Formula Weight 369.3g/mol
Solubility Aqueous solutions (unstable above pH 6.0)
Content And Storage Hygroscopic
Form Solid
Quantity 250 mg
Purity 95% by elemental analysis