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MilliporeSigma™ Calbiochem™ Methotrexate

Catalog No. 454126100MG
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454126100MG 100 mg
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Catalog No. 454126100MG Supplier MilliporeSigma™ Supplier No. 454126100MG

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Description

Inhibits thymidylate synthetase, is a nonselective de novo purine synthesis inhibitor, and has a significant toxicity profile including hepatotoxicity, pneumonitis, and bone marrow suppress

Inhibits thymidylate synthetase, is a nonselective de novo purine synthesis inhibitor, and has a significant toxicity profile including hepatotoxicity, pneumonitis, and bone marrow suppression. Potent folic acid antagonist. Induces apoptosis in HL-60 human leukemia cells. Also useful as an antitumor agent.

Specifications

Color Yellow
Description 98% by HPLC
Product Type Inhibitor
CAS 59-05-2
Molecular Formula C20H22N8O5·3H2O
Formula Weight 508.5g/mol
Solubility DMSO
Content And Storage Protect from light
Form Solid
Quantity 100 mg