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MilliporeSigma™ Calbiochem™ Methotrexate
Inhibits thymidylate synthetase, is a nonselective de novo purine synthesis inhibitor, and has a significant toxicity profile including hepatotoxicity, pneumonitis, and bone marrow suppress
Supplier: MilliporeSigma™ 454126100MG
Description
Inhibits thymidylate synthetase, is a nonselective de novo purine synthesis inhibitor, and has a significant toxicity profile including hepatotoxicity, pneumonitis, and bone marrow suppression. Potent folic acid antagonist. Induces apoptosis in HL-60 human leukemia cells. Also useful as an antitumor agent.Specifications
| Yellow | |
| 59-05-2 | |
| 508.5g/mol | |
| Protect from light | |
| 100 mg |
| 98% by HPLC | |
| C20H22N8O5·3H2O | |
| DMSO | |
| Solid |