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MilliporeSigma™ Calbiochem™ Glyburide

A sulfonylurea that selectively blocks ATP-sensitive K+ channels.

Supplier:  MilliporeSigma™ 3563101GM

Catalog No. 3563101GM


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Description

Description

A sulfonylurea that selectively blocks ATP-sensitive K+ channels. Reduced K+ conductance causes membrane depolarization and influx of Ca2+ through voltage sensitive Ca2+ channels. Blocks vascular smooth muscle relaxation produced by KATP channel openers. Inhibits the vasorelaxing effects of nitric oxide.
Specifications

Specifications

White
ATP-sensitive K+ channels
C23H28ClN3O5S
DMSO or EtOH (slightly)
1 g
98% by TLC
10238-21-8
494g/mol
Solid
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