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MilliporeSigma™ Calbiochem™ Emetine, Dihydrochloride

Catalog No. 324693250MG
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250 mg
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324693250MG 250 mg
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Catalog No. 324693250MG Supplier MilliporeSigma™ Supplier No. 324693250MG
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Description

Principal alkaloid of ipecac, isolated from the ground roots of Uragoga ipecacuanha.

Principal alkaloid of ipecac, isolated from the ground roots of Uragoga ipecacuanha . Irreversibly blocks protein synthesis in eukaryotes by inhibiting the movement of ribosomes along the mRNA. Induces hypotension by blocking adrenoreceptors. Interferes with cytometric analysis of DNA replication at the early S phase. Also identified as a specific inhibitor of HIF-2α protein stability and transcriptional activity (IC50 ≤1μM.

Specifications

Color White with a Faint Yellow Cast
Description 98% by HPLC and Titration (dried basis) (perchloric acid method)
Target Proteins Movement of ribosomes along the mRNA
CAS 316-42-7
Molecular Formula C29H40N2O4·2HCl
Formula Weight 553.6g/mol
Solubility EtOH or H2O
Content And Storage Hygroscopic, Protect from light
Form Solid
Quantity 250 mg