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MilliporeSigma™ Calbiochem™ Dexamethasone

Catalog No. 265005100MG
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Quantity:
100 mg
Catalog No. Quantity
265005100MG 100 mg
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Catalog No. 265005100MG

Supplier: MilliporeSigma™ 265005100MG

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Description

Most active and highly stable glucocorticoid.

Most active and highly stable glucocorticoid. Causes a reduction in cyclin A and Cdk2 activity, and inhibition of G1/S transition in osteoblasts. Inhibits the phosphorylation of retinoblastoma (Rb) protein. Inhibits the expression of inducible but not constitutive nitric oxide synthase in vascular endothelial cells (IC50 = 5 nM). Enhances active cation transport in aortic smooth muscle cells by stimulating the Na+ - K+ pump. Induces apoptosis in human thymocytes.

Specifications

Color White
Description 99% by TLC
Target Proteins Phosphorylation of rb protein
CAS 50-02-2
Molecular Formula C22H29FO5
Formula Weight 392.5g/mol
Solubility DMSO, CHCl3 or EtOH
Form Solid
Quantity 100 mg