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MilliporeSigma™ Calbiochem™ Ru360
A cell-permeable oxygen-bridged dinuclear ruthenium amine complex that has been shown to bind to mitochondria with high affinity (Kd = 340 pM).
$439.00 - $1,070.00
Specifications
| Color | Reddish Brown |
|---|---|
| Target Proteins | Ca2+ uptake into mitochondria in vitro |
| Molecular Formula | C2H26Cl3N8O5Ru2 |
| Formula Weight | 550.8g/mol |
| Solubility | deoxygenated H2O |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity | |||||
|
55-744-01SET
|
MilliporeSigma™
5574401SET |
1 Set |
N/A
|
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|
55-744-0500UG
|
MilliporeSigma™
557440500UG |
500 μg |
N/A
|
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Description
A cell-permeable oxygen-bridged dinuclear ruthenium amine complex that has been shown to bind to mitochondria with high affinity (Kd = 340 pM). Specifically blocks Ca2+ uptake into mitochondria in vitro (IC50 = 184 pM) and in situ in intact myocytes (complete block after incubation with ∽10μM of Ru360 for 30 min). Does not affect other cellular Ca2+ transport processes involved in cardiac muscle contraction, even at micromolar levels.Specifications
| Reddish Brown | |
| C2H26Cl3N8O5Ru2 | |
| deoxygenated H2O | |
| Solid |
| Ca2+ uptake into mitochondria in vitro | |
| 550.8g/mol | |
| Hygroscopic, Protect from light | |
| 97% by capillary electrophoresis |