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MilliporeSigma™ Calbiochem™ 4-Hydroxynonenal
Description
A major aldehyde product formed by peroxidation of ω-6-unsaturated fatty acids that is regarded as a specific marker of lipid peroxidation. Inhibits proliferation and induces differentiation of HL-60 human leukemic cells. Also induces cell death in murine alveolar macrophages and in PC12 cells. An inhibitor of state 3 respiration at micromolar levels. Causes a transient increase in cytosolic Ca2+ and irreversibly inhibits Na+, K+-ATPase activity (IC50 = 120μM). Acts as a reversible inhibitor of c-Jun N-terminal kinase (JNK).
Spécifications
Spécifications
| Formulation | Supplied at 10mg/mL in ethanol |
| Description | 98% by HPLC |
| Target Proteins | Na+, K+-ATPase activity |
| CAS | 75899-68-2 |
| Molecular Formula | C9H16O2 |
| Formula Weight | 156.2g/mol |
| Form | Liquid |
| Quantity | 1 mg |