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Tocris Bioscience™ BIO

Catalog No. 319450
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Quantity:
10 mg
50 mg
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Catalog No. Quantity
319450 50 mg
319410 10 mg
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Catalog No. 319450 Supplier Tocris Bioscience™ Supplier No. 3194/50
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Description

Potent GSK-3 inhibitor; also inhibits cdks

Potent ATP-competitive glycogen synthase kinase-3 (GSK-3) inhibitor (IC50 = 5 nM). Also inhibits cyclin-dependent kinases (cdks; IC50 values are <100 nM for cdk2 and 5 and sub micromolar for cdk1, cdk4 and cdk9). Maintains self-renewal and pluripotency in embryonic stem cells via activation of the Wnt signaling pathway in vitro; also promotes proliferation and dedifferentiation in cardiomyocytes.

Negative Control also available.

Chemical Identifiers

CAS 667463-62-9
Molecular Formula C16H10BrN3O2

Specifications

Quantity 50 mg
Formula Weight 356.17
Purity >98%
Molecular Weight (g/mol) 356.179
Chemical Name or Material BIO

Safety and Handling

Recommended Storage Store at +4°C