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  5. Tocris Bioscience™ Bexarotene

Tocris Bioscience™ Bexarotene

Numéro de catalogue. 581950
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50 mg
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Numéro de catalogue. Quantity
581950 50 mg
581910 10 mg
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Numéro de catalogue. 581950 Fournisseur Tocris Bioscience™ Code fournisseur 5819/50
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Description

Potent and selective RXR agonist

Bexarotene is a potent and selective RXR agonist (EC50 values are 24, 25 and 33 nM for RXRβ, RXRγ and RXRα, respectively). Exhibits >300-fold selectivity for RXR over RAR receptors. Inhibits tumor cell invasion and migration in vitro, and inhibits metastasis and angiogenesis in mouse models. Also promotes brown adipogenic differentiation and induces brown adipogenic reprogramming from myoblasts.

Spécifications

Chemical Name or Material 4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid
CAS 153559-49-0
Synonym LGD 1069
Quantity 50 mg
Target Retinoid X Receptor Agonists
Molecular Formula C24H28O2
Formula Weight 348.48
Purity >99%