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Tocris Bioscience™ BAY 60-6583

Catalog No. 447210
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50 mg
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447210 10 mg
447250 50 mg
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Catalog No. 447210 Supplier Tocris Bioscience™ Supplier No. 4472/10
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Description

Potent A2B receptor agonist; cardioprotective

Potent adenosine A2B receptor agonist (EC50 = 2.83 nM for murine A2B receptor). Displays selectivity for A2B over A1, A2A and A3 receptors. Decreases fMLP-induced superoxide production in neutrophils at low concentrations (1-10 nM). Cardioprotective; attenuates infarct size in a mouse model of myocardial ischemia. Exhibits ERK1/2-biased agonism.

Chemical Identifiers

CAS 910487-58-0
Molecular Formula C19H17N5O2S

Specifications

Quantity 10 mg
Formula Weight 379.44
Purity >98%
Molecular Weight (g/mol) 379.438
Chemical Name or Material BAY 60-6583

Safety and Handling

Recommended Storage Store at +4°C