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Invitrogen™ BAD Polyclonal Antibody
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Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA517896

Numéro de catalogue. PIPA517896


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Description

Description

It is not recommended to aliquot this antibody. This antibody is not cross-reactive with related proteins.

The protein encoded by BAD is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Spécifications

Identifiants chimiques

BAD
-20°C
Polyclonal
Liquid
IgG
Human, Mouse, Rat, Monkey
BAD
AI325008; BAD; Bbc2; Bbc6; Bcl2 antagonist of cell death; BCL2 associated agonist of cell death; bcl-2 associated death agonist; Bcl2-antagonist of cell death; BCL2-antagonist of cell death protein; bcl2-associated agonist of cell death; bcl2-associated death promoter; bcl-2-binding component 6; BCL2-binding component 6; BCL2-binding protein; BCL2L8; bcl2-L-8; Bcl-2-like protein 8; BCL-X/BCL-2 binding protein; bcl-XL/Bcl-2-associated death promoter; hypothetical protein LOC615013; OTTMUSP00000017561; OTTMUSP00000022400
BAD
Primary
Antigen affinity chromatography
57 μg/mL
Immunoprecipitation, Western Blot
Unconjugated
Rabbit
RUO
0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
O35147, Q61337, Q92934
12015, 572, 64639
Synthetic peptide corresponding to residues surrounding Ser112 of mouse Bad.
Antibody

Spécifications

BAD
Polyclonal
Unconjugated
BAD
AI325008; BAD; Bbc2; Bbc6; Bcl2 antagonist of cell death; BCL2 associated agonist of cell death; bcl-2 associated death agonist; Bcl2-antagonist of cell death; BCL2-antagonist of cell death protein; bcl2-associated agonist of cell death; bcl2-associated death promoter; bcl-2-binding component 6; BCL2-binding component 6; BCL2-binding protein; BCL2L8; bcl2-L-8; Bcl-2-like protein 8; BCL-X/BCL-2 binding protein; bcl-XL/Bcl-2-associated death promoter; hypothetical protein LOC615013; OTTMUSP00000017561; OTTMUSP00000022400
Rabbit
Antigen affinity chromatography
RUO
12015, 572, 64639
-20°C
Liquid
Immunoprecipitation, Western Blot
57 μg/mL
0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
O35147, Q61337, Q92934
BAD
Synthetic peptide corresponding to residues surrounding Ser112 of mouse Bad.
100 μL
Primary
Human, Mouse, Rat, Monkey
Antibody
IgG
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