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Tocris Bioscience™ AZ 3146

Catalog No. 399450
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10 mg
50 mg
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Catalog No. Quantity
399450 50 mg
399410 10 mg
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Catalog No. 399450 Supplier Tocris Bioscience™ Supplier No. 3994/50

Description

Potent and selective Mps1 kinase inhibitor

Potent and selective monopolar spindle 1 (Mps1) kinase inhibitor (IC50 = 35 nM). Displays selectivity over 46 other kinases including Cdk1 and aurora kinase B. Interferes with chromosome alignment and overrides spindle assembly checkpoint. Inhibits the recruitment of Mad1, Mad2 and centromere protein E (CENP-E) to kinetochores.

Chemical Identifiers

CAS 1124329-14-1
Molecular Formula C24H32N6O3

Specifications

Quantity 50 mg
Formula Weight 452.55
Purity >99%
Molecular Weight (g/mol) 452.559
Chemical Name or Material AZ 3146

Safety and Handling

Recommended Storage Store at +4°C