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Thermo Scientific Chemicals Aurora Kinase/Cdk Inhibitor
Supplier: Thermo Scientific Chemicals J65997LB0
Description
Aurora Kinase/Cdk Inhibitor is a broad spectrum inhibitor of cyclin-dependent kinases and aurora kinases including CDK1/Cyclin B, CDK2/Cyclin A, CDK2/Cyclin E, Aurora-A and Aurora-B. It as been shown to induce growth suppression and mitotic defects, these results suggest that Aurora Kinase/Cdk Inhibitor could be useful for cell cycle analysis and therapy of various cancers, including Ewing's sarcoma.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Specifications
| 5 mg | |
| 2°C to 8°C | |
| 443797-96-4 | |
| 435.41 | |
| Light Sensitive | |
| Aurora Kinase/Cdk Inhibitor | |
| KDKUVYLMPJIGKA-UHFFFAOYSA-N | |
| 4-{[5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-yl]amino}benzene-1-sulfonamide |
| White | |
| A cell-permeable triazolylsulfonamido compound that acts a reversible, ATP-competitive kinase inhibitor with selectivities towards Aurora kinases | |
| C15H12F2N6O3S | |
| 4-(5-Amino-1-(2,6-difluorobenzoyl)-1H-[1,2,4]triazol-3-ylamino)-benzenesulfonamide; | |
| Soluble in DMSO at 15mg/ml | |
| Powder | |
| NC1=NC(NC2=CC=C(C=C2)S(N)(=O)=O)=NN1C(=O)C1=C(F)C=CC=C1F | |
| 394.36 |
Chemical Identifiers
| 443797-96-4 | |
| 394.36 | |
| 4-(5-Amino-1-(2,6-difluorobenzoyl)-1H-[1,2,4]triazol-3-ylamino)-benzenesulfonamide; | |
| NC1=NC(NC2=CC=C(C=C2)S(N)(=O)=O)=NN1C(=O)C1=C(F)C=CC=C1F |
| C15H12F2N6O3S | |
| KDKUVYLMPJIGKA-UHFFFAOYSA-N | |
| 4-{[5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-yl]amino}benzene-1-sulfonamide |
Safety and Handling
Recommended Storage : Keep cold; Store under Argon
RUO – Research Use Only