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Invitrogen™ ATG16L1 Recombinant Rabbit Monoclonal Antibody (23GB665)
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Numéro de catalogue. MA553658
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MA553658 100 μL
MA553659 20 μL
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Numéro de catalogue. MA553658 Fournisseur Invitrogen™ Code fournisseur MA553658

Rabbit Recombinant Monoclonal Antibody

ATG16L1 Recombinant Monoclonal Antibody for Western Blot, ICC/IF, Flow

Autophagy related protein 16 L is encoded by the ATG16L gene and is located on chromosome 2 in humans. It is also known as WD30 or IBD10 (Inflammatory Bowel Disease 10). ATG 12 and ATG5 conjugate with each other and undergoes homo oligomerisation with ATG16L to form an 800 kDa complex called the Atg16L complex. This complex facilitates coupling or lipidation of LC3 to phosphatidylethanolamine (PE) and this ubiquitin-like conjugation system is a widely used marker for autophagy. However, the ATG 16L complex along with other ATGs like ATG 18 and ATG 21 prevent the premature cleavage of ATG8-PE by the cysteine protease, Atg4 until the autophagosome is deemed complete.

Spécifications

Antigène ATG16L1
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 23GB665
Concentration 1 mg/mL
Conjugué Unconjugated
Formule PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gène ATG16L1
Numéro d’acquisition du gène Q676U5, Q8C0J2
Alias du gène 1500009K01Rik; A16L1; APG 16-L1; Apg16l; APG16L beta; APG16L isoforms 1; APG16-like 1; atg16; ATG16 autophagy related 16-like 1; ATG16A; Atg16l; Atg16l1; Atg16L1 gamma; autophagy related 16 like 1; autophagy related 16-like 1; autophagy related 16-like 1 (S. cerevisiae); autophagy-related 16-like 1; autophagy-related 16-like 1 gamma; autophagy-related protein 16-1; hCG_1817841; IBD10; UNQ9393/PRO34307; WD repeat domain 30; Wdr30
Symboles de gène ATG16L1
Espèces hôtes Rabbit
Immunogène A synthetic peptide of human ATG16L1 (1-150AA).
Méthode de purification Affinity chromatography
Quantité 100 μL
Statut réglementaire RUO
Primaire ou secondaire Primary
ID du gène (Entrez) 363278, 55054, 77040
Espèces cibles Human, Mouse, Rat
Contenu et stockage -20°C
Type de produit Antibody
Forme Liquid
Isotype IgG
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