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A kinase (PRKA) anchor protein 13, Mouse, Clone: 3D6, Abnova™
Mouse monoclonal antibody raised against a partial recombinant AKAP13.
Supplier: Abnova Corporation H00011214M10
Description
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in at least 3 transcript variants encoding different isoforms containing a dbl oncogene homology (DH) domain and a pleckstrin homology (PH) domain. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins, resulting in the conversion of the inactive GTPase to the active form capable of transducing signals. The PH domain has multiple functions. Therefore, these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway and, in addition, function as protein kinase A-anchoring proteins. [provided by RefSeq
Sequence: MKLNPQQAPLYGDCVVTVLLAEEDKAEDDVVFYLVFLGSTLRHCTSTRKVSSDTLETIAPGHDCCETVKVQLCASKEGLPVFVVAEEDFHFVQDEAYDAAQFLATSAGNQSpécifications
| A kinase (PRKA) anchor protein 13 | |
| Monoclonal | |
| Unconjugated | |
| PBS with no preservative; pH 7.4 | |
| NM_006738 | |
| AKAP13 | |
| AKAP13 (NP_006729, 1 a.a. ∼ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| 100 μg | |
| Yes | |
| 11214 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
| IgG2b κ |
| ELISA, Immunohistochemistry (PFA fixed), Western Blot | |
| 3D6 | |
| Mouse monoclonal antibody raised against a partial recombinant AKAP13. | |
| AKAP13 | |
| AKAP-Lbc/ARHGEF13/BRX/FLJ11952/FLJ43341/HA-3/Ht31/LBC/PROTO-LB/PROTO-LBC/c-lbc | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Human, Rat | |
| Antibody |