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Invitrogen™ ANKLE2 Polyclonal Antibody

Description
Recommended positive controls: 293T, Jurkat, Raji. Predicted reactivity: Human (99%), Mouse (84%), Rat (83%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
Spécifications
Spécifications
| Antigen | ANKLE2 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7 |
| Gene | ANKLE2 |
| Gene Accession No. | Q86XL3 |
| Gene Alias | 1110001J12Rik; Ab2-034; AI661024; Ankle2; ankyrin repeat and LEM domain containing 2; ankyrin repeat and LEM domain-containing protein 2; D5Ertd585e; Kiaa0692; LEM domain containing 7; LEM domain-containing protein 4; LEM4; LEMD7; liver regeneration-related protein LRRG057; MCPH16; RGD1310191 |
| Gene Symbols | ANKLE2 |
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