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Tocris Bioscience™ Amlexanox

Catalog No. 485750
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10 mg
50 mg
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Catalog No. Quantity
485750 50 mg
485710 10 mg
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Catalog No. 485750 Supplier Tocris Bioscience™ Supplier No. 4857/50
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Description

Selective inhibitor of TBK

Selective inhibitor of TANK-binding kinase 1 (TBK1) and IKKε (IC50 values are ∽1-2 μM). Displays no effect on IKKα or IKKβ at these concentrations. Reversibly lowers weight, increases insulin sensitivity, and reduces inflammation and steatosis in three mouse models of obesity. Exhibits antiallergic activity; inhibits the release of histamine from rat mast cells. Also binds to Hsp90 and inhibits C-terminal chaperone activity in vitro.

Chemical Identifiers

CAS 68302-57-8
Molecular Formula C16H14N2O4

Specifications

Quantity 50 mg
Formula Weight 298.29
Purity >99%
Molecular Weight (g/mol) 298.30
Chemical Name or Material Amlexanox

Safety and Handling

Recommended Storage Store at -20°C