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Tocris Bioscience™ AM 80

Catalog No. 350710
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50 mg
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Catalog No. Quantity
350710 10 mg
350750 50 mg
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Description

RARα agonist; anticancer agent

Retinoic acid receptor α (RARα) agonist that induces differentiation (ED50 = 0.79 nM) and apoptosis of HL-60 cells in vitro. Exhibits antiproliferative effects against a variety of human tumor cells lines (mean values of 35, 40 and 60% growth inhibition at 0.1, 1 and 10 μM respectively) and displays anticancer activity against acute promyelocytic leukemia in vivo.

Chemical Identifiers

CAS 94497-51-5
Molecular Formula C22H25NO3

Specifications

Quantity 10 mg
Formula Weight 351.44
Purity >99%
Molecular Weight (g/mol) 351.45
Chemical Name or Material AM 80

Safety and Handling

Recommended Storage Store at Room Temperature