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Invitrogen™ ADORA2A Polyclonal Antibody

Description
PA1-042 detects adenosine receptor A2a (A2aAR) in human, rat, mouse and canine tissues. This antibody does not detect other AR subtypes. PA1-042 has been successfully used in Western blot, ICC/IF, immunohistochemistry and immunoprecipitation procedures. By Western blot, this antibody detects an ~45 kDa protein from canine striatum representing A2aAR. Immunohistochemical staining of A2aAR in human hippocampus with PA1-042 yields a pattern consistent with plasma membrane staining. The PA1-042 immunogen is a synthetic peptide corresponding to residues E(373) S H G D M G L P D V E L L S H E L K(391) of canine A2aAR.
ADORA2A is a protein which is one of several receptor subtypes for adenosine. The activity of the encoded protein, a G-protein coupled receptor family member, is mediated by G proteins which activate adenylyl cyclase. This protein is abundant in basal ganglia, vasculature and platelets and it is a major target of caffeine.
Spécifications
Spécifications
| Antigène | ADORA2A |
| Applications | Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.69 mg/mL |
| Conjugué | Unconjugated |
| Formule | PBS with 1 mg/mL BSA and 0.05% sodium azide |
| Gène | ADORA2A |
| Numéro d’acquisition du gène | P11617, P29274, P30543, Q60613 |
| Alias du gène | A2a receptor; A2AAR; A2aR; AA2AR; ADENO; adenosine A2a receptor; Adenosine A2a-receptor; adenosine receptor A2a; adenosine receptor subtype A2a; ADORA2; ADORA2A; Adora2l1; AR; hA2aR; RDC8; unnamed protein product |
| Symboles de gène | ADORA2A |
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