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Invitrogen™ ACVR2B Polyclonal Antibody
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Numéro de catalogue. PIPA528231
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Quantité:
100 μL
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Numéro de catalogue. Quantité
PIPA528231 100 μL
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Numéro de catalogue. PIPA528231 Fournisseur Invitrogen™ Code fournisseur PA528231

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Description

Rabbit Polyclonal Antibody

Recommended positive controls: U87-MG, SK-N-SH, IMR-32, SK-N-AS, mosue cerebellum, mouse testis, ACVR2B-transfected 293T. Predicted reactivity: Mouse (99%), Rat (99%), Pig (100%), Chicken (89%), Bovine (97%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

ACVR2B is a type II member of the TGF-beta family of receptor ser/thr kinases and is involved in the activin and myostatin signaling pathway. Activins and inhibins are members of the TGF-beta superfamily due to amino acid homology with respect to the conservation of 7 of the 9 cysteine residues common to all TGF-beta forms. To date, seven type I and five type II activin receptors have been cloned from mammals, including activin receptor IA, activin receptor IIA, activin receptor IB, and activin receptor IIB. In addition, two splice variants of activin receptor IIA and five splice variants of activin receptor IIB have been reported.

Spécifications

Antigène ACVR2B
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.45 mg/mL
Conjugué Unconjugated
Formule PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gène ACVR2B
Numéro d’acquisition du gène P27040, Q13705
Alias du gène activin A receptor type 2B; activin A receptor type IIB; activin A receptor, type IIB; activin receptor IIB; activin receptor type IIB; Activin receptor type-2B; Activine receptor 2b (transmembrane serine kinase); ActRIIB; ACTR-IIB; ActRIIB type II activin receptor B; ACVR2B; HTX4; MGC116908
Symboles de gène ACVR2B
Espèces hôtes Rabbit
Immunogène Recombinant protein encompassing a sequence within the center region of human Activin Receptor Type IIB. The exact sequence is proprietary.
Méthode de purification Antigen affinity chromatography
Quantité 100 μL
Statut réglementaire RUO
Primaire ou secondaire Primary
ID du gène (Entrez) 11481, 93
Espèces cibles Human, Mouse
Contenu et stockage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Type de produit Antibody
Forme Liquid
Isotype IgG
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