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  7. 6-Thioguanine, 98%

6-Thioguanine, 98%

Catalog No. AAB2128003
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Quantity:
1 g
5 g
Catalog No. Quantity
AAB2128003 1 g
AAB2128006 5 g
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Catalog No. AAB2128003

Supplier: Thermo Scientific Chemicals B2128003

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Description

CAS: 154-42-7 | C5H5N5S | 167.19 g/mol

6-Thioguanine acts as an antineoplastic and purine antimetabolite. It is also useful as an inhibition of stimulated expression of TNF-related apoptosis-inducing ligand (TRAIL) protein. It is involved in the treatment of acute leukemias and Psoriasis. Further, it is used for the treatment of ulcerative colitis and autoimmune diseases.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in dilute solutions of alkali hydroxides and hot alcohol. Insoluble in water.

Notes
Incompatible with strong oxidizing agents.

Chemical Identifiers

CAS 154-42-7
Molecular Formula C5H5N5S
Molecular Weight (g/mol) 167.19
MDL Number MFCD00233553
InChI Key WYWHKKSPHMUBEB-UHFFFAOYSA-N
Synonym 6-thioguanine, thioguanine, tioguanine, 2-amino-6-mercaptopurine, 6-mercaptoguanine, tioguanin, tabloid, lanvis, 2-amino-6-purinethiol, 2-aminopurine-6-thiol
PubChem CID 2723601
ChEBI CHEBI:9555
SMILES NC1=NC(=S)C2=C(N1)N=CN2

Specifications

Melting Point >360°C
Assay Percent Range 0.98
Quantity 1 g
UN Number UN2811
Beilstein 157765
Merck Index 14,9337
Solubility Information Soluble in dilute solutions of alkali hydroxides and hot alcohol. Insoluble in water.
IUPAC Name 2-amino-3,7-dihydropurine-6-thione
Formula Weight 167.19
Percent Purity 98%
Chemical Name or Material 6-Thioguanine
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Safety and Handling

Hazard Category H301-H341
Hazard Statement GHS H Statement
H301
Precautionary Statement P201-P202-P264b-P270-P281-P301+P310-P308+P313-P330-P501c
DOTInformation Transport Hazard Class: 6.1; Packing Group: III; Proper Shipping Name: TOXIC SOLIDS, ORGANIC, N.O.S.
EINECSNumber 205-827-2
RTECSNumber UP0740000
TSCA No
Recommended Storage Ambient temperatures

RUO – Research Use Only