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  6. 6-Aminohexanoic acid, 99%

6-Aminohexanoic acid, 99%

Catalog No. AAA1471936
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AAA1471936 500 g
AAA147190E 2500 g
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Catalog No. AAA1471936 Supplier Thermo Scientific Chemicals Supplier No. A1471936
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This chemical may require us to obtain additional information for our regulatory and chemical compliance records. If required, we will contact you for this information once your order is placed.

Description

6-aminohexanoic acid, CAS # 60-32-2, is a synthetic lysine derivative with inhibitory activity against fibrinolysis. It shows hematologic activity. | CAS: 60-32-2 | C6H13NO2 | 131.175 g/mol

6-Aminohexanoic acid is used as an intermediate in the polymerization of Nylon-6. It is involved in the extraction of aldehydes from the reaction mixture as well as to improve the solubilization of membrane proteins in electrophoresis. It acts as an inhibitor of fibrinolysis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • 6-aminohexanoic acid, an epsilon-amino acid, shows an antifibrinolytic and hematologic activity
  • This compound competitively inhibits the activation of plasminogen; it consequently reduces the conversion of plasminogen to plasmin (fibrinolysin), an enzyme responsible for the degradation of fibrin clots, fibrinogen, and other plasma proteins, including the procoagulant factors V and VIII

Application

  • It has been used as an intermediate in the polymerization of Nylon-6
  • It is used for biomolecular applications to extract aldehydes from the reaction mixture and to increase membrane protein solubilization in electrophoresis experiments
  • It has been described to inhibit plasminogen binding to activated platelets
  • This compound can bind and inactivate carboxypeptidase B
  • This compound can also inhibit the activation of the first component of the complement system

Chemical Identifiers

CAS 60-32-2
Molecular Formula C6H13NO2
Molecular Weight (g/mol) 131.175
MDL Number MFCD00008238
InChI Key SLXKOJJOQWFEFD-UHFFFAOYSA-N
Synonym 6-aminocaproic acid, aminocaproic acid, amicar, epsikapron, capramol, caprocid, epsamon, eaca, acepramin, caprolisin
PubChem CID 564
ChEBI CHEBI:16586
IUPAC Name 6-aminohexanoic acid
SMILES C(CCC(=O)O)CCN

Specifications

Melting Point 210°C to 212°C
Assay Percent Range ≥99%
Linear Formula H2N(CH2)5CO2H
Quantity 500 g
Beilstein 906872
Merck Index 14,432
Solubility Information Soluble in water. Slightly soluble in alcohol. Practically insoluble in ether and chloroform.
Formula Weight 131.18
Percent Purity 99%
Chemical Name or Material 6-Aminohexanoic acid

Safety and Handling

Hazard Category H315-H319-H335
Hazard Statement GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber 200-469-3
RTECSNumber MO6300000
TSCA Yes
Recommended Storage Ambient temperatures

RUO – Research Use Only